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KMID : 0363220120500040367
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Korean Journal of Dermatology
2012 Volume.50 No. 4 p.367 ~ p.370
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Cutaneous Angiosarcoma Developed at Site of Herpes Zoster Scar: Wolf`s Isotopic Response
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Cho Hyun-Hee
Paik Seung-Hwan
Byun Hee-Jin
Cho Kwang-Hyun
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Abstract
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Angiosarcoma is a rare malignant vascular tumor of endothelial origin. It can involve any organ, including the skin, soft tissue, liver, bone, spleen, and orbit. Skin is the most frequent site of primary angiosarcoma, however, metastatic skin involvement of angiosarcoma is exceptional. Wolf’s isotopic response implies that the new disease appeared at the site of an already healed skin disease. Several types of cutaneous lesions have been described, occurring within cleared cutaneous herpes zoster, or herpes simplex lesions. These lesions include comedones, granulomatous diseases, tinea, furunculosis, wart, psoriasis, pseudolymphoma, leukemia, lymphoma, basal cell carcinoma, squamous cell carcinoma and cutaneous metastases, from internal carcinoma. Herein, we report a case of cutaneous angiosarcoma of unknown origin that has developed at the site of a scar, after herpes zoster in a 79-year-old man as isotopic response.
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KEYWORD
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Angiosarcoma, Herpes zoster, Wolf`s isotopic response
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